Color
Normal urine usually ranges from a light yellow to a dark amber color
that may vary according to the concentration and the type of food and drugs
that are ingested. The color of urine is attributed to its chief pigment, "urochrome".
Changes in urine may be due to disease, but can also be caused by food and
drugs ingested.
Transparency
Freshly voided urine is usually clear. Samples exposed to room
temperature
for more than an hour or two may become cloudy bur to bacterial growth or
precipitation of phosphates or urates. Possible transparency are the
presence of kidney stones, bacteria, sperm, yeasts, or stool contamination.
Odor
The odor of a fresh urine sample is normally Aromatic. The odor, when
unusual (Ammonia-like sweet and fruity), may be due to a urinary tract
infection, or the presence of ketone bodies as in Diabetes, starvation,
strenuous exercise, vomiting, diarrhea, malnutrition; or may be due to the
ingestion of certain food or to the contamination of the urine container.
Specific Gravity
The specific gravity of urine depends on the gravity and number of
molecules dissolved in solution of the urine sample. The normal urinary
specific gravity may range from 1.002 to 1.030. Most of the molecules
dissolved in the urine are made of Sodium Chloride and Urea. Urine is
usually More concentrated in the morning which, is a normal phenomenon.
Abnormally diluted urine may be present in kidney disease whereas very
concentrated urine with high specific gravity may be present in diabetes,
vomiting, diarrhea, and fever.
Leukocytes
Leukocytes are one of the white (Leuko) cells (Cytes) present in blood
stream which defend the body from bacterial invasion. When present in the
urine may suggest the presence of an underlying mild urinary tract
infection. A repeated presence of leukocytes indicate the needs for further
testing such as cultures or blood test.
Nitrates
The presence of nitrates in the urine is due to the conversion of
nitrates in food by the action of the bacteria. Therefore, a positive
nitrate test is a good indicator for the presence of a significant amount of
bacteria in urine. This may be associated with a urinary tract infection of
a bladder or urethral the tube which connects the bladder to the outside)
infection. Significant bacteriuria is estimated to affect 1%-2% of young
girls,5%-10% of pregnant women and is also associated with diabetes,
hypertension, herniation of the urinary bladder, Prostate problems and the
use of a catheter for drawing certain anatomic abnormalities.
Ph
Normally freshly voided urine is acid. Therefore, the PH which is a
measure of acidity may range from 4.0-7.0. People who eat high protein diets
produce a more acid urine than those that consume mostly fruits and
vegetables. Increased urinary acidity (lower PH) may also be present in
diabetes, fever, pulmonary emphysema, diarrhea and dehydration. Alkaline PH
(Higher PH) may also be noted in chronic inflammation of the urinary
bladder, acute or chronic kidney failure, or for intoxication of salicylate
( such as aspirin) or other drugs.
Proteins
The presence of proteins in the urine is called "Proteinuria" and is an
important sign of renal disease. Proteinuria can be due to an increased
permeability of the walls of the filtering components of the kidneys (The
glomerulus). Proteins may be present in a number of kidney diseases. However
a small amount of proteins, mostly albumin, may appear in the urine in
response to excessive muscular exertion, exposure to colds, or with extra
ingestion of proteins with food. In some people the presence of proteins in
the urine may occur upon arising from a sitting position. This is called "
Orthostatic Proteinuria". Proteinuria may also be present in acute
inflammation of the kidneys as acute nephritis, or in the presence of
malignant hypertension, heart failure and diabetes.
Ketones
Ketones are called "Ketone bodies" and include acetone, diacetic acid and
beta hydrobutyric acid and and appear in normal urine of patients on a
carbohydrate-deficent diet. When the body can not find sufficient sugar for
its metabolism it turns to its fat stores for energy which in turn are
reduced to ketone bodies. Ketone bodies appear in urine before they increase
significantly in blood and this is called "Ketonuria". The presence of
ketones in the urine may occur in uncontrolled diabetes and hyperthyroidism.